Synthesis 2009(1): 148-154  
DOI: 10.1055/s-0028-1083282
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Complementary Reactions of Allylic Carbamates Using Palladium(II): Formation of Oxazolidinones or Allylic Amides from a Common Precursor

Steven D. R. Christie*a, Adam D. Warringtona, Christopher J. Lunnissb
a Departmentt of Chemistry, Loughborough University, Loughborough, LE11 3RF, UK
Fax: +44(1509)223925; e-Mail: s.d.christie@lboro.ac.uk;
b GlaxoSmithKline, Gunnels Wood Road, Stevenage, SG1 2NY, UK
Further Information

Publication History

Received 24 October 2008
Publication Date:
12 December 2008 (online)

Abstract

The use of palladium to effect two different reactions on a common starting material is presented. With a copper oxidant, an aminohalogenation is achieved to produce oxazolidinones. When the copper is absent, a [3,3]-sigmatropic rearrangement takes place to produce allylic amides.