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DOI: 10.1055/s-0044-1788048
Success of Combination Therapy with Isavuconazole in a Pediatric Patient with Breakthrough Invasive Aspergillosis
Funding/Support The author(s) received no financial support for the research, authorship, and/or publication of this article.![](https://www.thieme-connect.de/media/10.1055-s-00029028/202404/lookinside/thumbnails/10-1055-s-0044-1788048_2400006-1.jpg)
Abstract
The increasing incidence of invasive fungal infections, coupled with the growing population of immunocompromised patients, has led to an increased need for antifungal agents. The newest azole, isavuconazole, plays an important role in the treatment of invasive aspergillosis in adults due to its broad spectrum, tolerability, and no need for therapeutic drug monitoring. This agent, which has not yet been approved for use in children, has significant problems with drug supply in Türkiye. We present the treatment response to isavuconazole combination therapy used in salvage treatment in a patient with breakthrough invasive aspergillosis, who had treatment failure with different antifungal combination treatment options and surgical resection.
Role of Funder/Sponsor (if any)
None.
Publication History
Received: 11 January 2024
Accepted: 12 June 2024
Article published online:
08 July 2024
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