Download PDF
Planta Med 2003; 69(3): 254-257
DOI: 10.1055/s-2003-38484
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

New Diterpenoids from the Aerial Parts of Salvia candelabrum

Judit Hohmann1 , Gábor Janicsák2 , Peter Forgo3 , Dóra Rédei1 , Imre Máthé1 , 2 , Tibor Bartók4
  • 1Department of Pharmacognosy, University of Szeged, Szeged, Hungary
  • 2Institute of Ecology and Botany of the Hungarian Academy of Sciences, Vácrátót, Hungary
  • 3Department of Organic Chemistry, University of Szeged, Szeged, Hungary
  • 4Cereal Research Non-Profit Company, Szeged, Hungary
Further Information

Publication History

Received: June 24, 2002

Accepted: November 16, 2002

Publication Date:
04 April 2003 (online)

    Permissions and Reprints

Abstract

The new diterpenoids, candesalvoquinone, 12-O-methylcandesalvone B, candesalvone B methyl ester with the 3,4-secoabietane skeleton, and candelabroquinone with the abietane skeleton were isolated from the aerial parts of Salvia candelabrum, together with the known compound candelabrone. The structures were established by mass spectroscopy and advanced two-dimensional NMR methods, including 1H-NMR, JMOD, 1H-1H COSY, HSQC, HMBC and NOESY experiments.

Key words

Salvia candelabrum - Lamiaceae - abietane diterpenoids - seco-abietane diterpenoids - candelabrone

References

  • 1 Adezet T, Canigueral S, Iglesias J, Manso D. Some flavonoid compounds of Salvia candelabrum .  Planta Med. 1986;  52 525-6
    PubMedGoogle Scholar
  • 2 Canigueral S, Iglesias H, Sanchez-Ferrando F, Virgili A. Candelabrone, a new abietane diterpene from the leaves of Salvia candelabrum .  Phytochemistry. 1988;  27 221-4
    CrossrefPubMedGoogle Scholar
  • 3 Mendes E, Marco J L, Rodríguez B, Jimeno M L, Lobo A M, Prabhakar S. Diterpenoids from Salvia candelabrum .  Phytochemistry. 1989;  28 1685-90
    CrossrefPubMedGoogle Scholar
  • 4 Canigueral S, Iglesias J, Vila R, Ibanez C. The leaf essential oil of Salvia candelabrum Boiss.  Flavour Fragr J. 1989;  4 135-7
    PubMedGoogle Scholar
  • 5 Zupkó I, Hohmann J, Rédei D, Falkay G y, Janicsák G, Máthé I. Antioxidant activity of leaves of Salvia species in enzyme-dependent and enzyme-independent systems of lipid peroxidation and their phenolic constituents.  Planta Med. 2001;  67 366-8
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Nagy G, Günther G, Máthé I, Blunden G, Yang M H, Crabb T A. 12-Deoxy-6,7-dehydroroyleanone, 12-deoxy-6-hydroxy-6,7-dehydroroyleanone and 12-deoxy-7,7-dimethoxy-6-ketoroyleanone from Salvia nutans roots.  Phytochemistry. 1999;  51 809-12
    CrossrefPubMedGoogle Scholar
  • 7 Ali M S, Dardass A KY, Ahmad S, Saleem M, Firdous S, Ahmad V U. Two new diterpenes from Salvia triloba .  Fitoterapia. 2000;  71 347-52
    CrossrefPubMedGoogle Scholar
  • 8 Li M, Zhang J S, Ye Y M, Fang J N. Constituents of the roots of Salvia prionitis .  J Nat Prod. 2000;  63 139-41
    CrossrefPubMedGoogle Scholar
  • 9 Lin H C, Ding H Y, Chang W L. Two new fatty diterpenoids from Salvia miltiorrhiza .  J Nat Prod. 2001;  64 648-50
    CrossrefPubMedGoogle Scholar
  • 10 Lin H C, Chang W L. Diterpenoids from Salvia miltiorrhiza .  Phytochemistry. 2000;  53 951-3
    CrossrefPubMedGoogle Scholar

Dr. Judit Hohmann

Department of Pharmacognosy

University of Szeged

P. O. Box 121

6701 Szeged

Hungary

Fax: +36-62-545704

Email: hohmann@pharma.szote.u-szeged.hu

      >