Planta Med 2003; 69(3): 274-277
DOI: 10.1055/s-2003-38479
Letter
© Georg Thieme Verlag Stuttgart · New York

Antibacterial Activity and Chemical Composition of Essential Oil of Chrysanthemum boreale

Kang-Ju Kim1 , Young-Hoi Kim2 , Hyeon-Hee Yu3 , Seung-Il Jeong1 , Jung-Dan Cha1 , Bong-Seop Kil4 , Yong-Ouk You3
  • 1Department of Oral Microbiology, School of Dentistry, Wonkwang University, Iksan, Korea
  • 2KT&G Central Research Institute, Taejon, Korea
  • 3Department of Oral Biochemistry and VCRC, School of Dentistry, Wonkwang University, Iksan, Korea
  • 4Division of Life Science, College of Natural Science, Wonkwang University, Iksan, Korea
Further Information

Publication History

Received: June 11, 2002

Accepted: October 27, 2002

Publication Date:
04 April 2003 (online)

Abstract

The essential oil of Chrysanthemum boreale Makino was analyzed by means of GC and GC-MS. Eighty-seven constituents were identified, representing 94.13 % of the total oil and the major components were camphor, α-thujone, cis-chrysanthenol, 1,8-cineole, α-pinene, and β-caryophyllene. Furthermore, the essential oil exhibited antibacterial activity (MIC, more than 800 μg/mL versus 0.125 μg/mL for ampicillin) after it was tested against 6 Gram(+) bacteria and 8 Gram(-) bacteria.

References

  • 1 Mangena T, Muyima N Y. Comparative evaluation of the antimicrobial activities of essential oils of Artemisia afra, Pteronia incana and Rosmarinus officinalis on selected bacteria and yeast strains.  Letters in Applied Microbiology. 1999;  28 291-6
  • 2 Marino M, Bersani C, Comi G. Impedance measurements to study the antimicrobial activity of essential oils from Lamiaceae and Compositae .  International Journal of Food Microbiology. 2001;  67 187-95
  • 3 Fine D H, Furgang D, Barnett M L, Drew C, Steinberg L, Charles C H,. et al . Effect of an essential oil-containing antiseptic mouth-rinse on plaque and salivary Streptococcus mutans levels.  Journal of Clinical Periodontology. 2000;  27 157-61
  • 4 Kim J K. Illustrated natural drugs encyclopedia. Seoul; Namsandang Publishers 1989: 59
  • 5 Jang D S, Yang M S, Ha T J, Park K H. Structural analogues of cumambrin B from the flower of Chrysanthemum boreale .  Archives of Pharmacal Research. 1998;  21 591-4
  • 6 Khallouki F, Hmamouchi M, Younos C, Soulimani R, Bessiere J M, Essassi E M. Antibacterial and molluscicidal activities of the essential oil of Chrysanthemum viscidehirtum .  Fitoterapia. 2000;  71 544-6
  • 7 Alvarez-Castellanos P P, Bishop C D, Pascual-Villalobos M J. Antifungal activity of the essential oil of flowerheads of garland chrysanthemum (Chrysanthemum coronarium) against agricultural pathogens.  Phytochemistry. 2001;  57 99-102
  • 8 Chang S T, Chen P F, Chang S C. Antibacterial activity of leaf essential oils and their constituents from Cinnamomum osmophloeum .  Journal of Ethnopharmacology. 2001;  77 123-7
  • 9 Tzakou O, Pitarokili D, Chinou I B, Harvala C. Composition and antimicrobial activity of the essential oil of Salvia ringens .  Planta Medica. 2001;  67 81-3
  • 10 Martins A P, Salgueiro L R, Goncalves M J, Vila R, Tomi F, Adzet T. et al . Casanova J. Antimicrobial activity and chemical composition of the bark oil of Croton stellulifer, an endemic species from S. Tome e Principe.  Planta Medica. 2000;  66 647-50
  • 11 Magiatis P, Melliou E, Skaltsounis A L, Chinou I B, Mitaku S. Chemical composition and antimicrobial activity of the essential oils of Pistacia lentiscus var. chia .  Planta Medica. 1999;  65 749-52
  • 12 Cobos M I, Rodriguez J L, Oliva M L, Demo M, Faillaci S M, Zygadlo J A. Composition and antimicrobial activity of the essential oil of Baccharis notosergila .  Planta Medica. 2001;  67 84-6

Prof. Dr. Yong-Ouk You

Department of Oral Biochemistry

School of Dentistry

Wonkwang University

344-2 Shinyong-dong

Iksan

Jeonbuk 570-749

Korea

Email: hope7788@wonkwang.ac.kr

Fax: +82-63-850-7157

    >