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Planta Med 1999; 65(5): 432-436
DOI: 10.1055/s-1999-14086
Original Paper

Georg Thieme Verlag Stuttgart · New York

Simultaneous Determination of Lipo-Alkaloids Extracted from Aconitum carmiechaeli Using Electrospray Ionization Mass Spectrometry and Multiple Tandem Mass Spectrometry

Weixing Sun,, Fengrui Song,, Meng Cui, Shuying Liu
  • Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P.R. China
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Publication History

September 7, 1998

March 14, 1999

Publication Date:
31 December 1999 (online)

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Abstract

Electrospray ionization mass spectrometry (ESI-MS) combined with multiple tandem mass spectrometry (MSn) has been applied for simultaneously determining lipo-alkaloids from the aconite tubers. ESI-MS can give a very good mass separation for lipo-alkaloid mixture and MSn can provide structural information. Accordingly, structures were assigned to 12 known lipo-alkaloids including lipoaconitines, lipomesaconitines, lipodeoxyaconitines, and lipohypaconitines on the base of the information obtained using MS n. Also, four new lipo-alkaloids were found and their structures were interpreted using the MSn data.

Key words:

Lipo-alkaloids - aconitines - Aconitum carmiechaeli - Ranunculaceae - ESI-MS - MSn

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