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Planta Med 1978; 33(4): 385-388
DOI: 10.1055/s-0028-1097397
DOI: 10.1055/s-0028-1097397
Research Articles
© Georg Thieme Verlag Stuttgart · New York
Mallorepine, Cyano–γ–Pyridone from Mallotus repandus
Further Information
Publication History
Publication Date:
13 January 2009 (online)
Abstract
The methanol extract of a Formosan folklore drug, the aerial part of Mallotus répandus (Euphorbiaceae), has been fractionated monitored by the antiulcerogenic activity to give, together with bergenin as one of the active principles, a crystalline substance for which the name mallorepine is given. Mallorepine has been identified as 3–cyano–1–methyl–4–pyridone (I) but has been shown to be inactive in inhibiting the formation of the stress–induced gastric ulcers. Mallorepine may propably be an intermediate on the biosynthetic pathway from nicotinamide (II) to ricinine (III).
Key Word Index
Mallotus répandus - Mallorepine - Cyano–γ–pyridone